Additionally, CD47 blocking antibodies inhibit proliferation of unstimulated astrocytoma cells but not normal astrocytes.
2.
Blocking antibodies have been described as a mechanism for HSV-1 to evade the immune system.
3.
The blocking antibody BMS-936559 has been shown to bind to PD-L1 and prevent its binding to PD-1.
4.
The antibody that fails to react is known as the blocking antibody and prevents the precipitating antibody from binding to the antigens.
5.
However, when the serum is diluted, the blocking antibody is as well and its concentration decreases enough for the proper precipitation reaction to occur.
6.
Several teams have reported that injecting women with immunoglobulins ( which seem to trigger production of blocking antibodies ) can improve pregnancy and birthrates.
7.
The role of CD47 in cell migration was first demonstrated for neutrophils, where CD47 blocking antibodies inhibited transmigration of neutrophils and monocytes through the endothelium.
8.
Inhibition of Aurora B function by RNA interference or microinjection of blocking antibodies impairs the alignment of chromosomes at the equator of the mitotic spindle.
9.
The appearance of foreign molecules on the placenta normally prompts the mother's body to produce " blocking antibodies, " which effectively hide the baby from her immune system.
10.
The diagnosis of MG can also be confirmed with blood work that measures the amount of blocking antibody present, but only 70 % of ocular MG patients have detectable antibody levels.
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